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Absolute protein quantitation of the mouse macrophage Toll-like receptor and chemotaxis pathways
The Toll-like receptor (TLR) and chemotaxis pathways are key components of the innate immune system. Subtle variation in the concentration, timing, and molecular structure of the ligands are known to affect downstream signaling and the resulting immune response. Computational modeling and simulation...
Autores principales: | Manes, Nathan P., Calzola, Jessica M., Kaplan, Pauline R., Fraser, Iain D. C., Germain, Ronald N., Meier-Schellersheim, Martin, Nita-Lazar, Aleksandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374760/ https://www.ncbi.nlm.nih.gov/pubmed/35961990 http://dx.doi.org/10.1038/s41597-022-01612-y |
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