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Comparison of characteristics and tumor targeting properties of extracellular vesicles derived from primary NK cells or NK-cell lines stimulated with IL-15 or IL-12/15/18

NK cell-based therapies have shown promise for hematological cancer forms, but their use against solid tumors is hampered by their poor ability to infiltrate the tumor. NK cells release extracellular vesicles (EVs) containing cytolytic proteins, indicating that NK-cell derived EVs may have therapeut...

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Detalles Bibliográficos
Autores principales: Aarsund, Miriam, Segers, Filip M., Wu, Yunjie, Inngjerdingen, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374793/
https://www.ncbi.nlm.nih.gov/pubmed/35119498
http://dx.doi.org/10.1007/s00262-022-03161-0