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ORP5 and ORP8 orchestrate lipid droplet biogenesis and maintenance at ER–mitochondria contact sites

Lipid droplets (LDs) are the primary organelles of lipid storage, buffering energy fluctuations of the cell. They store neutral lipids in their core that is surrounded by a protein-decorated phospholipid monolayer. LDs arise from the endoplasmic reticulum (ER). The ER protein seipin, localizing at E...

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Detalles Bibliográficos
Autores principales: Guyard, Valentin, Monteiro-Cardoso, Vera Filipa, Omrane, Mohyeddine, Sauvanet, Cécile, Houcine, Audrey, Boulogne, Claire, Ben Mbarek, Kalthoum, Vitale, Nicolas, Faklaris, Orestis, El Khallouki, Naima, Thiam, Abdou Rachid, Giordano, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375143/
https://www.ncbi.nlm.nih.gov/pubmed/35969857
http://dx.doi.org/10.1083/jcb.202112107