Cargando…

The gateway to guanine nucleotides: Allosteric regulation of IMP dehydrogenases

Inosine 5′‐monophosphate dehydrogenase (IMPDH) is an evolutionarily conserved enzyme that mediates the first committed step in de novo guanine nucleotide biosynthetic pathway. It is an essential enzyme in purine nucleotide biosynthesis that modulates the metabolic flux at the branch point between ad...

Descripción completa

Detalles Bibliográficos
Autores principales: Buey, Rubén M., Fernández‐Justel, David, Jiménez, Alberto, Revuelta, José L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375230/
https://www.ncbi.nlm.nih.gov/pubmed/36040265
http://dx.doi.org/10.1002/pro.4399