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Synthetically recoded virus sCPD9 – A tool to accelerate SARS-CoV-2 research under biosafety level 2 conditions

Research with infectious SARS-CoV-2 is complicated because it must be conducted under biosafety level 3 (BSL-3) conditions. Recently, we constructed a live attenuated SARS-CoV-2 virus by rational design through partial recoding of the SARS-CoV-2 genome and showed that the attenuated virus, designate...

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Detalles Bibliográficos
Autores principales: Kunec, Dusan, Osterrieder, Nikolaus, Trimpert, Jakob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375251/
https://www.ncbi.nlm.nih.gov/pubmed/35992535
http://dx.doi.org/10.1016/j.csbj.2022.08.027