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Targeting purine metabolism in ovarian cancer

Purine, an abundant substrate in organisms, is a critical raw material for cell proliferation and an important factor for immune regulation. The purine de novo pathway and salvage pathway are tightly regulated by multiple enzymes, and dysfunction in these enzymes leads to excessive cell proliferatio...

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Detalles Bibliográficos
Autores principales: Liu, Jingchun, Hong, Shasha, Yang, Jiang, Zhang, Xiaoyi, Wang, Ying, Wang, Haoyu, Peng, Jiaxin, Hong, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375293/
https://www.ncbi.nlm.nih.gov/pubmed/35964092
http://dx.doi.org/10.1186/s13048-022-01022-z