Mendelian randomization of circulating proteome identifies actionable targets in heart failure

BACKGROUND: Heart failure (HF) is a prevalent cause of mortality and morbidity. The molecular drivers of HF are still largely unknown. RESULTS: We aimed to identify circulating proteins causally associated with HF by leveraging genome-wide genetic association data for HF including 47,309 cases and 9...

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Detalles Bibliográficos
Autores principales: Moncla, Louis-Hippolyte Minvielle, Mathieu, Samuel, Sylla, Mame Sokhna, Bossé, Yohan, Thériault, Sébastien, Arsenault, Benoit J., Mathieu, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375407/
https://www.ncbi.nlm.nih.gov/pubmed/35964012
http://dx.doi.org/10.1186/s12864-022-08811-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375407/
https://www.ncbi.nlm.nih.gov/pubmed/35964012
http://dx.doi.org/10.1186/s12864-022-08811-2

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