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Mendelian randomization of circulating proteome identifies actionable targets in heart failure

BACKGROUND: Heart failure (HF) is a prevalent cause of mortality and morbidity. The molecular drivers of HF are still largely unknown. RESULTS: We aimed to identify circulating proteins causally associated with HF by leveraging genome-wide genetic association data for HF including 47,309 cases and 9...

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Detalles Bibliográficos
Autores principales:	Moncla, Louis-Hippolyte Minvielle, Mathieu, Samuel, Sylla, Mame Sokhna, Bossé, Yohan, Thériault, Sébastien, Arsenault, Benoit J., Mathieu, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375407/ https://www.ncbi.nlm.nih.gov/pubmed/35964012 http://dx.doi.org/10.1186/s12864-022-08811-2

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