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Assessing and enhancing foldability in designed proteins

Recent advances in protein‐design methodology have led to a dramatic increase in reliability and scale. With these advances, dozens and even thousands of designed proteins are automatically generated and screened. Nevertheless, the success rate, particularly in design of functional proteins, is low...

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Detalles Bibliográficos
Autores principales: Listov, Dina, Lipsh‐Sokolik, Rosalie, Rosset, Stéphane, Yang, Che, Correia, Bruno E., Fleishman, Sarel Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375437/
https://www.ncbi.nlm.nih.gov/pubmed/36040259
http://dx.doi.org/10.1002/pro.4400