Candesartan Cilexetil Attenuates Arrhythmogenicity Following Pressure Overload in Rats via the Modulation of Cardiac Electrical and Structural Remodeling and Calcium Handling Dysfunction

BACKGROUND: Cardiac hypertrophy is associated with abnormal electrophysiology and increased arrhythmia risk. This study assessed whether candesartan cilexetil, an angiotensin II type 1 receptor blocker, could suppress arrhythmogenecity by attenuating cardiac electrical remodeling and calcium mishand...

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Detalles Bibliográficos
Autores principales: Chang, Gwo‐Jyh, Yeh, Yung‐Hsin, Chen, Wei‐Jan, Ko, Yu‐Shien, Lai, Ying‐Ju, Lee, Yun‐Shien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375482/
https://www.ncbi.nlm.nih.gov/pubmed/35862154
http://dx.doi.org/10.1161/JAHA.121.024285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375482/
https://www.ncbi.nlm.nih.gov/pubmed/35862154
http://dx.doi.org/10.1161/JAHA.121.024285

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