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Label-Free Mass Spectrometry-Based Quantitative Proteomics to Evaluate the Effects of the Calcium-Sensing Receptor Agonist Cinacalcet on Protein Expression in Rat Brains and Livers

BACKGROUND: Cinacalcet is a calcium-sensing receptor agonist that is clinically approved for the treatment of secondary hyperparathyroidism in chronic kidney disease and hypercalcemia in patients with parathyroid carcinoma. This study aimed to use quantitative mass spectrometry-based label-free prot...

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Detalles Bibliográficos
Autores principales: Bulska, Ewa, Gawor, Andrzej, Konopka, Anna, Wryk, Grzegorz, Czarkowska-Pączek, Bożena, Gajewski, Zdzisław, Pączek, Leszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375513/
https://www.ncbi.nlm.nih.gov/pubmed/35941808
http://dx.doi.org/10.12659/MSM.937338