Crystal structure of SARS‐CoV‐2 nsp10–nsp16 in complex with small molecule inhibitors, SS148 and WZ16

SARS‐CoV‐2 nsp10–nsp16 complex is a 2′‐O‐methyltransferase (MTase) involved in viral RNA capping, enabling the virus to evade the immune system in humans. It has been considered a valuable target in the discovery of antiviral therapeutics, as the RNA cap formation is crucial for viral propagation. T...

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Detalles Bibliográficos
Autores principales: Klima, Martin, Khalili Yazdi, Aliakbar, Li, Fengling, Chau, Irene, Hajian, Taraneh, Bolotokova, Albina, Kaniskan, H. Ümit, Han, Yulin, Wang, Ke, Li, Deyao, Luo, Minkui, Jin, Jian, Boura, Evzen, Vedadi, Masoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Full‐length Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375521/
https://www.ncbi.nlm.nih.gov/pubmed/36040262
http://dx.doi.org/10.1002/pro.4395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375521/
https://www.ncbi.nlm.nih.gov/pubmed/36040262
http://dx.doi.org/10.1002/pro.4395

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