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Impact of genetic polymorphisms at the promoter area of IL-10 gene on tacrolimus level in Jordanian renal transplantation recipients

BACKGROUND: Tacrolimus is a widely used immunosuppressant that prevents solid organ transplant rejection. The pharmacokinetics of Tacrolimus show considerable varia - bility. Interleukin-10 (IL-10), in the host's immune response after transplantation, contributes to the variable CYP3Adependent...

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Detalles Bibliográficos
Autores principales: Khaleel, Bara'ah, Yousef, Al-Motassem, Al-Zoubi, Mazhar Salim, Al-Ulemat, Muhammad, Masadeh, Ahmad A., Abuhaliema, Ali, Al-Batayneh, Khalid M., Al-Trad, Bahaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Medical Biochemists of Serbia, Belgrade 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375538/
https://www.ncbi.nlm.nih.gov/pubmed/36042898
http://dx.doi.org/10.5937/jomb0-33343