MiR-190 ameliorates glucotoxicity-induced dysfunction and apoptosis of pancreatic β-cells by inhibiting NOX2-mediated reactive oxygen species production

Glucotoxicity-induced pancreatic β-cell failure contributes to the development of type 2 diabetes mellitus (T2DM). Accumulating evidence reveals that miRNAs play a critical role in regulating pancreatic β-cell function and survival. In this study, we employed a self-assembled cell microarray (SAMcel...

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Detalles Bibliográficos
Autores principales: Lu, Huinan, Yang, Junyu, Li, Juan, Yuan, Huiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375543/
https://www.ncbi.nlm.nih.gov/pubmed/35971429
http://dx.doi.org/10.7717/peerj.13849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375543/
https://www.ncbi.nlm.nih.gov/pubmed/35971429
http://dx.doi.org/10.7717/peerj.13849

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