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Upregulation of PD-1 Expression and High sPD-L1 Levels Associated with COVID-19 Severity

COVID-19 has several mechanisms that can lead to lymphocyte depletion/exhaustion. The checkpoint inhibitor molecule programmed death protein 1 (PD-1) and its programmed death-ligand 1 (PDL-1) play an important role in inhibiting cellular activity as well as the depletion of these cells. In this stud...

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Detalles Bibliográficos
Autores principales: Beserra, Danielle Rosa, Alberca, Ricardo Wesley, Branco, Anna Claudia Calvielli Castelo, de Mendonça Oliveira, Luana, de Souza Andrade, Milena Mary, Gozzi-Silva, Sarah Cristina, Teixeira, Franciane Mouradian Emidio, Yendo, Tatiana Mina, da Silva Duarte, Alberto José, Sato, Maria Notomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375698/
https://www.ncbi.nlm.nih.gov/pubmed/35971391
http://dx.doi.org/10.1155/2022/9764002