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Berberine Reduces Renal Cell Pyroptosis in Golden Hamsters with Diabetic Nephropathy through the Nrf2-NLRP3-Caspase-1-GSDMD Pathway

OBJECTIVE: To observe the effect of berberine (BBR) on kidney cell pyroptosis in golden hamsters with diabetic nephropathy (DN) and to explore the molecular mechanism of its renal protection. METHODS: Fifty clean-grade male golden hamsters were randomly divided into a control group (10) and a model...

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Detalles Bibliográficos
Autores principales: Ding, Baozhu, Geng, Songyan, Hou, Xiaojie, Ma, Xuelian, Xu, Huazhou, Yang, Fan, Liu, Kun, Liang, Wenjie, Ma, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375700/
https://www.ncbi.nlm.nih.gov/pubmed/35971382
http://dx.doi.org/10.1155/2021/5545193