Two major genes associated with autoimmune arthritis, Ncf1 and Fcgr2b, additively protect mice by strengthening T cell tolerance

A breach of T cell tolerance is considered as a major step in the pathogenesis of rheumatoid arthritis. In collagen-induced arthritis (CIA) model, immunization with type II collagen (COL2) leads to arthritis in mice through T cells responding to the immunodominant COL2(259–273) peptide. T cells coul...

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Detalles Bibliográficos
Autores principales: Li, Qijing, Zhong, Jianghong, Luo, Huqiao, Urbonaviciute, Vilma, Xu, Zhongwei, He, Chang, Holmdahl, Rikard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375767/
https://www.ncbi.nlm.nih.gov/pubmed/35963953
http://dx.doi.org/10.1007/s00018-022-04501-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375767/
https://www.ncbi.nlm.nih.gov/pubmed/35963953
http://dx.doi.org/10.1007/s00018-022-04501-0

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