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D-dopachrome tautomerase drives astroglial inflammation via NF-κB signaling following spinal cord injury
BACKGROUND: Reactive astrocytes are increasingly recognized as crucial regulators of innate immunity in degenerative or damaged central nervous system (CNS). Many proinflammatory mediators have been shown to drive inflammatory cascades of astrocytes through activation of NF-κB, thereby affecting the...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375920/ https://www.ncbi.nlm.nih.gov/pubmed/35965310 http://dx.doi.org/10.1186/s13578-022-00867-7 |