NLRP3 inflammasome up-regulates major histocompatibility complex class I expression and promotes inflammatory infiltration in polymyositis

OBJECTIVE: This study was designed to investigate the role of the nucleotide-binding-domain -and leucine-rich repeat -containing (NLR) family, pyrin-domain-containing 3 (NLRP3) inflammasome in the pathogenesis of polymyositis (PM). METHODS: Immunochemistry was performed to analyze the NLRP3, caspase...

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Detalles Bibliográficos
Autores principales: Xia, Ping, Shao, Yu-Quan, Yu, Cong-Cong, Xie, Yu, Zhou, Zhi-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375941/
https://www.ncbi.nlm.nih.gov/pubmed/35965334
http://dx.doi.org/10.1186/s12865-022-00515-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375941/
https://www.ncbi.nlm.nih.gov/pubmed/35965334
http://dx.doi.org/10.1186/s12865-022-00515-2

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