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NLRP3 inflammasome up-regulates major histocompatibility complex class I expression and promotes inflammatory infiltration in polymyositis

OBJECTIVE: This study was designed to investigate the role of the nucleotide-binding-domain -and leucine-rich repeat -containing (NLR) family, pyrin-domain-containing 3 (NLRP3) inflammasome in the pathogenesis of polymyositis (PM). METHODS: Immunochemistry was performed to analyze the NLRP3, caspase...

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Detalles Bibliográficos
Autores principales:	Xia, Ping, Shao, Yu-Quan, Yu, Cong-Cong, Xie, Yu, Zhou, Zhi-Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375941/ https://www.ncbi.nlm.nih.gov/pubmed/35965334 http://dx.doi.org/10.1186/s12865-022-00515-2

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