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JIB-04, a histone demethylase Jumonji C domain inhibitor, regulates phenotypic switching of vascular smooth muscle cells

BACKGROUND: Vascular smooth muscle cell (VSMC) phenotype switching is critical for neointima formation, which is the major cause of restenosis after stenting or coronary artery bypass grafting. However, the epigenetic mechanisms regulating phenotype switching of VSMCs, especially histone methylation...

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Detalles Bibliográficos
Autores principales: He, Yi, Yi, Xin, Zhang, Zihao, Luo, Hanshen, Li, Rui, Feng, Xin, Fang, Ze-Min, Zhu, Xue-Hai, Cheng, Wenlin, Jiang, Ding-Sheng, Zhao, Fang, Wei, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375951/
https://www.ncbi.nlm.nih.gov/pubmed/35964071
http://dx.doi.org/10.1186/s13148-022-01321-8