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FACT modulates the conformations of histone H2A and H2B N-terminal tails within nucleosomes
Gene expression is regulated by the modification and accessibility of histone tails within nucleosomes. The histone chaperone FACT (facilitate chromatin transcription), comprising SPT16 and SSRP1, interacts with nucleosomes through partial replacement of DNA with the phosphorylated acidic intrinsica...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376062/ https://www.ncbi.nlm.nih.gov/pubmed/35963897 http://dx.doi.org/10.1038/s42003-022-03785-z |