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FACT modulates the conformations of histone H2A and H2B N-terminal tails within nucleosomes

Gene expression is regulated by the modification and accessibility of histone tails within nucleosomes. The histone chaperone FACT (facilitate chromatin transcription), comprising SPT16 and SSRP1, interacts with nucleosomes through partial replacement of DNA with the phosphorylated acidic intrinsica...

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Detalles Bibliográficos
Autores principales: Tsunaka, Yasuo, Ohtomo, Hideaki, Nishimura, Yoshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376062/
https://www.ncbi.nlm.nih.gov/pubmed/35963897
http://dx.doi.org/10.1038/s42003-022-03785-z