TDP-43 upregulates lipid metabolism modulator ABHD2 to suppress apoptosis in hepatocellular carcinoma

TAR DNA-Binding Protein 43 (TDP-43) has been well studied in neurodegenerative diseases, but its potential role in malignance is still unclear. Here, we demonstrate that TDP-43 contributes to the suppression of apoptosis by facilitating lipid metabolism in hepatocellular carcinoma (HCC). In HCC cell...

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Detalles Bibliográficos
Autores principales: Liu, Bo-wen, Wang, Xiang-yun, Cao, Jin-ling, Chen, Lu-lu, Wang, Yi-lei, Zhao, Bing-qian, Zhou, Jia, Shen, Zhi-fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376094/
https://www.ncbi.nlm.nih.gov/pubmed/35963893
http://dx.doi.org/10.1038/s42003-022-03788-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376094/
https://www.ncbi.nlm.nih.gov/pubmed/35963893
http://dx.doi.org/10.1038/s42003-022-03788-w

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