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ACSL4-dependent ferroptosis does not represent a tumor-suppressive mechanism but ACSL4 rather promotes liver cancer progression

Ferroptosis is a novel type of programmed cell death that differs from apoptosis in that it involves iron-dependent peroxidation of membrane phospholipids. Its role in a variety of human disorders, including cancer has been hypothesized in recent years. While it may function as an endogenous tumor s...

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Detalles Bibliográficos
Autores principales: Grube, Julia, Woitok, Marius Maximilian, Mohs, Antje, Erschfeld, Stephanie, Lynen, Celina, Trautwein, Christian, Otto, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376109/
https://www.ncbi.nlm.nih.gov/pubmed/35963845
http://dx.doi.org/10.1038/s41419-022-05137-5