Genetic basis of defects in immune tolerance underlying the development of autoimmunity

Genetic variants associated with susceptibility to autoimmune disease have provided important insight into the mechanisms responsible for the loss of immune tolerance and the subsequent development of autoantibodies, tissue damage, and onset of clinical disease. Here, we review how genetic variants...

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Detalles Bibliográficos
Autores principales: Hocking, Anne M., Buckner, Jane H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376219/
https://www.ncbi.nlm.nih.gov/pubmed/35979360
http://dx.doi.org/10.3389/fimmu.2022.972121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376219/
https://www.ncbi.nlm.nih.gov/pubmed/35979360
http://dx.doi.org/10.3389/fimmu.2022.972121

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