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Genetic basis of defects in immune tolerance underlying the development of autoimmunity
Genetic variants associated with susceptibility to autoimmune disease have provided important insight into the mechanisms responsible for the loss of immune tolerance and the subsequent development of autoantibodies, tissue damage, and onset of clinical disease. Here, we review how genetic variants...
Autores principales: | Hocking, Anne M., Buckner, Jane H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376219/ https://www.ncbi.nlm.nih.gov/pubmed/35979360 http://dx.doi.org/10.3389/fimmu.2022.972121 |
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