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FBP1 /miR-24-1/enhancer axis activation blocks renal cell carcinoma progression via Warburg effect

Warburg effect is a pivotal hallmark of cancers and appears prevalently in renal cell carcinoma (RCC). FBP1 plays a negative role in Warburg effect as a rate-limiting enzyme in gluconeogenesis, yet its mechanism in RCC remains to be further characterized. Herein, we revealed that FBP1 was downregula...

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Detalles Bibliográficos
Autores principales: Ju, Dongen, Liang, Ying, Hou, Guangdong, Zheng, Wanxiang, Zhang, Geng, Dun, Xinlong, Wei, Di, Yan, Fei, Zhang, Lei, Lai, Dong, Yuan, Jiarui, Zheng, Yu, Wang, Fuli, Meng, Ping, Wang, Yong, Yu, Wenqiang, Yuan, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376222/
https://www.ncbi.nlm.nih.gov/pubmed/35978816
http://dx.doi.org/10.3389/fonc.2022.928373