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Receptor tyrosine kinase (RTK) targeting in pediatric high-grade glioma and diffuse midline glioma: Pre-clinical models and precision medicine

Pediatric high-grade glioma (pHGG), including both diffuse midline glioma (DMG) and non-midline tumors, continues to be one of the deadliest oncologic diagnoses (both henceforth referred to as “pHGG”). Targeted therapy options aimed at key oncogenic receptor tyrosine kinase (RTK) drivers using small...

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Detalles Bibliográficos
Autores principales: Schwark, Kallen, Messinger, Dana, Cummings, Jessica R., Bradin, Joshua, Kawakibi, Abed, Babila, Clarissa M., Lyons, Samantha, Ji, Sunjong, Cartaxo, Rodrigo T., Kong, Seongbae, Cantor, Evan, Koschmann, Carl, Yadav, Viveka Nand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376238/
https://www.ncbi.nlm.nih.gov/pubmed/35978801
http://dx.doi.org/10.3389/fonc.2022.922928