Bioinstructive implantable scaffolds for rapid in vivo manufacture and release of CAR-T cells

Despite their clinical success, chimeric antigen receptor (CAR)-T cell therapies for B-cell malignancies are limited by lengthy, costly and labor-intensive ex vivo manufacturing procedures that may lead to cell products with heterogeneous composition. Here we describe an implantable, multifunctional...

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Detalles Bibliográficos
Autores principales: Agarwalla, Pritha, Ogunnaike, Edikan A., Ahn, Sarah, Froehlich, Kristen A., Jansson, Anton, Ligler, Frances S., Dotti, Gianpietro, Brudno, Yevgeny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376243/
https://www.ncbi.nlm.nih.gov/pubmed/35332339
http://dx.doi.org/10.1038/s41587-022-01245-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376243/
https://www.ncbi.nlm.nih.gov/pubmed/35332339
http://dx.doi.org/10.1038/s41587-022-01245-x

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