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Bioinstructive implantable scaffolds for rapid in vivo manufacture and release of CAR-T cells

Despite their clinical success, chimeric antigen receptor (CAR)-T cell therapies for B-cell malignancies are limited by lengthy, costly and labor-intensive ex vivo manufacturing procedures that may lead to cell products with heterogeneous composition. Here we describe an implantable, multifunctional...

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Detalles Bibliográficos
Autores principales:	Agarwalla, Pritha, Ogunnaike, Edikan A., Ahn, Sarah, Froehlich, Kristen A., Jansson, Anton, Ligler, Frances S., Dotti, Gianpietro, Brudno, Yevgeny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376243/ https://www.ncbi.nlm.nih.gov/pubmed/35332339 http://dx.doi.org/10.1038/s41587-022-01245-x

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