LCS-1 inhibition of superoxide dismutase 1 induces ROS-dependent death of glioma cells and degradates PARP and BRCA1

Gliomas are characterized by high morbidity and mortality, and have only slightly increased survival with recent considerable improvements for treatment. An innovative therapeutic strategy had been developed via inducing ROS-dependent cell death by targeting antioxidant proteins. In this study, we f...

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Detalles Bibliográficos
Autores principales: Ling, Min, Liu, Qing, Wang, Yufei, Liu, Xueting, Jiang, Manli, Hu, Jinyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376264/
https://www.ncbi.nlm.nih.gov/pubmed/35978820
http://dx.doi.org/10.3389/fonc.2022.937444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376264/
https://www.ncbi.nlm.nih.gov/pubmed/35978820
http://dx.doi.org/10.3389/fonc.2022.937444

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