Genomic alteration of MTAP/CDKN2A predicts sarcomatoid differentiation and poor prognosis and modulates response to immune checkpoint blockade in renal cell carcinoma

Sarcomatoid differentiation is a highly aggressive pathological characteristic of renal cell carcinoma (RCC) and is characterized by susceptibility to progression and extremely poor prognosis. In this study, we included all genomic alteration events that led to a loss of protein function of MTAP and...

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Detalles Bibliográficos
Autores principales: Xu, Wenhao, Anwaier, Aihetaimujiang, Liu, Wangrui, Wei, Gaomeng, Su, Jiaqi, Tian, Xi, Xia, Jing, Qu, Yuanyuan, Zhao, Jianyuan, Zhang, Hailiang, Ye, Dingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376285/
https://www.ncbi.nlm.nih.gov/pubmed/35979371
http://dx.doi.org/10.3389/fimmu.2022.953721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376285/
https://www.ncbi.nlm.nih.gov/pubmed/35979371
http://dx.doi.org/10.3389/fimmu.2022.953721

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