N1-methylpseudouridine found within COVID-19 mRNA vaccines produces faithful protein products

Synthetic mRNA technology is a promising avenue for treating and preventing disease. Key to the technology is the incorporation of modified nucleotides such as N1-methylpseudouridine (m1Ψ) to decrease immunogenicity of the RNA. However, relatively few studies have addressed the effects of modified n...

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Detalles Bibliográficos
Autores principales: Kim, Kyusik Q., Burgute, Bhagyashri D., Tzeng, Shin-Cheng, Jing, Crystal, Jungers, Courtney, Zhang, Junya, Yan, Liewei L., Vierstra, Richard D., Djuranovic, Sergej, Evans, Bradley S., Zaher, Hani S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376333/
https://www.ncbi.nlm.nih.gov/pubmed/35988540
http://dx.doi.org/10.1016/j.celrep.2022.111300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376333/
https://www.ncbi.nlm.nih.gov/pubmed/35988540
http://dx.doi.org/10.1016/j.celrep.2022.111300

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