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N1-methylpseudouridine found within COVID-19 mRNA vaccines produces faithful protein products
Synthetic mRNA technology is a promising avenue for treating and preventing disease. Key to the technology is the incorporation of modified nucleotides such as N1-methylpseudouridine (m1Ψ) to decrease immunogenicity of the RNA. However, relatively few studies have addressed the effects of modified n...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Author(s).
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376333/ https://www.ncbi.nlm.nih.gov/pubmed/35988540 http://dx.doi.org/10.1016/j.celrep.2022.111300 |