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Review: the role of GSDMD in sepsis

PURPOSE: Gasdermin D (GSDMD) is a cytoplasmic protein that is encoded by the gasdermin family GSDMD gene and is the ultimate executor of pyroptosis. Pyroptosis is a mode of lysis and inflammation that regulates cell death, ultimately leading to cell swelling and rupture. In sepsis, a dysregulated ho...

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Detalles Bibliográficos
Autores principales: Shao, Ruifei, Lou, Xiran, Xue, Jinfang, Ning, Deyuan, Chen, Guobing, Jiang, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376580/
https://www.ncbi.nlm.nih.gov/pubmed/35969260
http://dx.doi.org/10.1007/s00011-022-01624-9