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A TLR4-independent critical role for CD14 in intracellular LPS sensing
Intracellular lipopolysaccharide (LPS) sensing by the noncanonical inflammasome comprising caspase-4 or −11 governs antibacterial host defense. How LPS gains intracellular access in vivo is largely unknown. Here, we show that CD14—an LPS-binding protein with a well-documented role in TLR4 activation...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376664/ https://www.ncbi.nlm.nih.gov/pubmed/35508125 http://dx.doi.org/10.1016/j.celrep.2022.110755 |