Regulation of PPAR-γ activity in lipid-laden hepatocytes affects macrophage polarization and inflammation in nonalcoholic fatty liver disease

BACKGROUND: Lipid metabolism disorder and inflammatory-immune activation are vital triggers in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). Various studies have shown that PPAR-γ exerts potent anti-inflammatory and immunomodulatory properties. However, little is known about the regu...

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Detalles Bibliográficos
Autores principales: Li, Xiao-Yun, Ji, Pei-Xuan, Ni, Xi-Xi, Chen, Yu-Xin, Sheng, Li, Lian, Min, Guo, Can-Jie, Hua, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376780/
https://www.ncbi.nlm.nih.gov/pubmed/36158922
http://dx.doi.org/10.4254/wjh.v14.i7.1365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376780/
https://www.ncbi.nlm.nih.gov/pubmed/36158922
http://dx.doi.org/10.4254/wjh.v14.i7.1365

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