Structural basis for Sarbecovirus ORF6 mediated blockage of nucleocytoplasmic transport

The emergence of heavily mutated SARS-CoV-2 variants of concern (VOCs) place the international community on high alert. In addition to numerous mutations that map in the spike protein of VOCs, expression of the viral accessory proteins ORF6 and ORF9b also elevate; both are potent interferon antagoni...

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Detalles Bibliográficos
Autores principales: Gao, Xiaopan, Tian, Huabin, Zhu, Kaixiang, Li, Qing, Hao, Wei, Wang, Linyue, Qin, Bo, Deng, Hongyu, Cui, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376891/
https://www.ncbi.nlm.nih.gov/pubmed/35970938
http://dx.doi.org/10.1038/s41467-022-32489-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376891/
https://www.ncbi.nlm.nih.gov/pubmed/35970938
http://dx.doi.org/10.1038/s41467-022-32489-5

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