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Side Chain Geometry Determines the Fibrillation Propensity of a Minimal Two-Beads-per-Residue Peptide Model

[Image: see text] The molecular mechanism of fibrillation is an important issue for understanding peptide aggregation. In our previous work, we demonstrated that the interchain attraction and intrachain bending stiffness control the aggregation kinetics and transient aggregate morphologies of a one-...

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Detalles Bibliográficos
Autores principales: Szała-Mendyk, Beata, Molski, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376954/
https://www.ncbi.nlm.nih.gov/pubmed/35917439
http://dx.doi.org/10.1021/acs.jpcb.2c03502