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An in silico Design, Expression and Purification of a Chimeric Protein as an Immunogen Candidate Consisting of IpaD, StxB, and TolC Proteins from Shigella spp.

BACKGROUND: Shigella spp. is the cause of dysentery and is widespread worldwide. On the other hand, antibiotic resistance is increasing in this bacterium. Bioinformatics is a new approach to vaccine and drug design involving the selection of appropriate antigens. This study aimed to design a chimeri...

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Detalles Bibliográficos
Autores principales: Fathi, Javad, Nazarian, Shahram, Kordbacheh, Emad, Hadi, Nahal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376997/
https://www.ncbi.nlm.nih.gov/pubmed/36061128
http://dx.doi.org/10.18502/ajmb.v14i3.9832