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Discovery of Desmuramylpeptide NOD2 Agonists with Single-Digit Nanomolar Potency

[Image: see text] The innate immune receptor nucleotide-binding oligomerization-domain-containing protein 2 (NOD2) represents an important target for the development of structurally defined small molecule immunomodulatory compounds that have great potential to be used either as vaccine adjuvants or...

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Detalles Bibliográficos
Autores principales: Guzelj, Samo, Bizjak, Špela, Jakopin, Žiga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377006/
https://www.ncbi.nlm.nih.gov/pubmed/35978688
http://dx.doi.org/10.1021/acsmedchemlett.2c00121