Prolonged FOS activity disrupts a global myogenic transcriptional program by altering 3D chromatin architecture in primary muscle progenitor cells

BACKGROUND: The AP-1 transcription factor, FBJ osteosarcoma oncogene (FOS), is induced in adult muscle satellite cells (SCs) within hours following muscle damage and is required for effective stem cell activation and muscle repair. However, why FOS is rapidly downregulated before SCs enter cell cycl...

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Detalles Bibliográficos
Autores principales: Barutcu, A. Rasim, Elizalde, Gabriel, Gonzalez, Alfredo E., Soni, Kartik, Rinn, John L., Wagers, Amy J., Almada, Albert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377060/
https://www.ncbi.nlm.nih.gov/pubmed/35971133
http://dx.doi.org/10.1186/s13395-022-00303-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377060/
https://www.ncbi.nlm.nih.gov/pubmed/35971133
http://dx.doi.org/10.1186/s13395-022-00303-x

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