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Hyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer’s disease

BACKGROUND: Progressive neuronal death is the key pathological feature of Alzheimer’s disease (AD). However, the molecular mechanisms underlying the neuronal death in AD patients have not been fully elucidated. Necroptosis reportedly activates and induces neuronal death in patients with Alzheimer’s...

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Detalles Bibliográficos
Autores principales: Dong, Yue, Yu, Hanqiao, Li, Xueqi, Bian, Kelong, Zheng, Yayuan, Dai, Mingrui, Feng, Xuejian, Sun, Yao, He, Yu, Yu, Bin, Zhang, Haihong, Wu, Jiaxin, Yu, Xianghui, Wu, Hui, Kong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377071/
https://www.ncbi.nlm.nih.gov/pubmed/35971179
http://dx.doi.org/10.1186/s12974-022-02567-y