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Therapeutic Effects of Tofacitinib on Pristane-Induced Murine Lupus

OBJECTIVES: This study aims to investigate the effectiveness of tofacitinib, a Janus kinase (JAK) 1/JAK3 inhibitor, in treating murine lupus, and also explore 12 related genes downstream of JAK-signal transducer and activator of transcription (STAT) signaling pathways to find the underlying mechanis...

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Detalles Bibliográficos
Autores principales: LIN, Jiayi, ZHANG, Yaqin, WANG, Meihua, ZHANG, Yang, LI, Pin, CAO, Yingping, YANG, Xuwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Turkish League Against Rheumatism 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377175/
https://www.ncbi.nlm.nih.gov/pubmed/36017210
http://dx.doi.org/10.46497/ArchRheumatol.2022.8252