Cargando…

Therapeutic Effects of Tofacitinib on Pristane-Induced Murine Lupus

OBJECTIVES: This study aims to investigate the effectiveness of tofacitinib, a Janus kinase (JAK) 1/JAK3 inhibitor, in treating murine lupus, and also explore 12 related genes downstream of JAK-signal transducer and activator of transcription (STAT) signaling pathways to find the underlying mechanis...

Descripción completa

Detalles Bibliográficos
Autores principales:	LIN, Jiayi, ZHANG, Yaqin, WANG, Meihua, ZHANG, Yang, LI, Pin, CAO, Yingping, YANG, Xuwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Turkish League Against Rheumatism 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377175/ https://www.ncbi.nlm.nih.gov/pubmed/36017210 http://dx.doi.org/10.46497/ArchRheumatol.2022.8252

Ejemplares similares

Maintenance of autoantibody production in pristane-induced murine lupus
por: Han, Shuhong, et al.
Publicado: (2015)

Pristane induced lupus mice as a model for neuropsychiatric lupus (NPSLE)
por: Yun, Yang, et al.
Publicado: (2023)

Disulfiram alleviates pristane-induced lupus via inhibiting GSDMD-mediated pyroptosis
por: Zhuang, Lili, et al.
Publicado: (2022)

Resveratrol Possesses Protective Effects in a Pristane-Induced Lupus Mouse Model
por: Wang, Zhuo-Long, et al.
Publicado: (2014)

Regulatory Effect of Melatonin on Cytokine Disturbances in the Pristane-Induced Lupus Mice
por: Zhou, Ling-ling, et al.
Publicado: (2010)

Basophils contribute to pristane-induced Lupus-like nephritis model
por: Dema, Barbara, et al.
Publicado: (2017)

Retinoic Acid Exerts Disease Stage-Dependent Effects on Pristane-Induced Lupus
por: Abdelhamid, Leila, et al.
Publicado: (2020)

Insufficient Iron Improves Pristane-Induced Lupus by Promoting Treg Cell Expansion
por: Gao, Xiaofei, et al.
Publicado: (2022)

Interferon Lambda Regulates Cellular and Humoral Immunity in Pristane-Induced Lupus
por: Aschman, Tom, et al.
Publicado: (2021)

Dependence on Autophagy for Autoreactive Memory B Cells in the Development of Pristane-Induced Lupus
por: Jang, Albert, et al.
Publicado: (2021)

Salvianolic acid A alleviates renal injury in systemic lupus erythematosus induced by pristane in BALB/c mice
por: Lin, Yihuang, et al.
Publicado: (2017)

Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model
por: Tumurkhuu, Gantsetseg, et al.
Publicado: (2020)

Fecal microbiota from MRL/lpr mice exacerbates pristane-induced lupus
por: Yi, Xiaoqing, et al.
Publicado: (2023)

Hypertension and endothelial dysfunction in the pristane model of systemic lupus erythematosus
por: McClung, Daniel M., et al.
Publicado: (2021)

Anti-complement factor H (CFH) autoantibodies could delay pristane-induced lupus nephritis
por: Li, Lin-Lin, et al.
Publicado: (2023)

Coptisine Alleviates Pristane-Induced Lupus-Like Disease and Associated Kidney and Cardiovascular Complications in Mice
por: Yan, Yu, et al.
Publicado: (2020)

Optogenetic stimulation of basal forebrain cholinergic neurons prevents neuroinflammation and neuropsychiatric manifestations in pristane induced lupus mice
por: Yun, Yang, et al.
Publicado: (2023)

NLRP3 Inflammasome Modulation by Melatonin Supplementation in Chronic Pristane-Induced Lupus Nephritis
por: Bonomini, Francesca, et al.
Publicado: (2019)

SPARC regulation of PMN clearance protects from pristane-induced lupus and rheumatoid arthritis
por: Sangaletti, Sabina, et al.
Publicado: (2021)

A novel monocyte differentiation pattern in pristane-induced lupus with diffuse alveolar hemorrhage
por: Han, Shuhong, et al.
Publicado: (2022)

Metformin improves FOXP3 mRNA expression through suppression of interferon gamma levels in pristane-induced murine models of lupus
por: Sumantri, Stevent, et al.
Publicado: (2021)

Effects by periodontitis on pristane-induced arthritis in rats
por: Eriksson, Kaja, et al.
Publicado: (2016)

Nigella sativa L. as immunomodulator and preventive effect on renal tissue damage of lupus mice induced by pristane
por: Hikmah, Zahrah, et al.
Publicado: (2022)

Effects of Dietary Oleacein Treatment on Endothelial Dysfunction and Lupus Nephritis in Balb/C Pristane-Induced Mice
por: Muñoz-García, Rocío, et al.
Publicado: (2023)

A novel NF-κB inhibitor, DHMEQ, ameliorates pristane-induced lupus in mice
por: QU, HUIQING, et al.
Publicado: (2014)

cGAS deficiency enhances inflammasome activation in macrophages and inflammatory pathology in pristane-induced lupus
por: Kumpunya, Sarinya, et al.
Publicado: (2022)

Leaky-gut enhanced lupus progression in the Fc gamma receptor-IIb deficient and pristane-induced mouse models of lupus
por: Thim-uam, Arthid, et al.
Publicado: (2020)

Induction of lupus-associated autoantibodies in BALB/c mice by intraperitoneal injection of pristane
Publicado: (1994)

Regulatory T Cells Compensation Failure Cause the Dysregulation of Immune Response in Pristane Induced Lupus Mice Model
por: Kalim, Handono, et al.
Publicado: (2018)

Galectin-3 orchestrates the histology of mesentery and protects liver during lupus-like syndrome induced by pristane
por: Lemos, F. S., et al.
Publicado: (2019)

Baicalein ameliorates pristane-induced lupus nephritis via activating Nrf2/HO-1 in myeloid-derived suppressor cells
por: Li, Dan, et al.
Publicado: (2019)

3β-Acetyloxy-oleanolic Acid Attenuates Pristane-Induced Lupus Nephritis by Regulating Th17 Differentiation
por: Zhou, Xiaoqing, et al.
Publicado: (2019)

CD4(+) T Cells Promote IgG Production in MHC-Independent and ICAM-1-Dependent Manners in Pristane-Induced Lupus Mice
por: Liu, Shuai, et al.
Publicado: (2022)

Qinghao-Biejia Herb Pair Alleviates Pristane-Induced Lupus-Like Disease and Associated Renal and Aortic Lesions in ApoE(−/−) Mice
por: Hong, Jiaze, et al.
Publicado: (2022)

Interleukin 6 Dependence of Anti-DNA Antibody Production: Evidence for Two Pathways of Autoantibody Formation in Pristane-induced Lupus
por: Richards, Hanno B., et al.
Publicado: (1998)

MicroRNA 155-deficiency leads to decreased autoantibody levels and reduced severity of nephritis and pneumonitis in pristane-induced lupus
por: Leiss, Harald, et al.
Publicado: (2017)

Oral tofacitinib citrate for recalcitrant cutaneous lupus
por: Bonnardeaux, Evelyne, et al.
Publicado: (2021)

Vasoactive intestinal peptide ameliorates renal injury in a pristane-induced lupus mouse model by modulating Th17/Treg balance
por: Fu, Dongdong, et al.
Publicado: (2019)

Regulation of Leukocyte Recruitment to the Spleen and Peritoneal Cavity during Pristane-Induced Inflammation
por: Li, Yu, et al.
Publicado: (2017)

CD38 promotes pristane-induced chronic inflammation and increases susceptibility to experimental lupus by an apoptosis-driven and TRPM2-dependent mechanism
por: García-Rodríguez, Sonia, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_boa2i8pei8t2oada76r8s42vp1