PARP1 inhibition elicits immune responses against non-small cell lung cancer

High levels of intracellular poly(ADP-ribose) (PAR) resulting from an elevated activity of PAR polymerase-1 (PARP1) correlate with poor infiltration of non-small cell lung cancers by cytotoxic T lymphocytes and dismal patient prognosis. Preclinical experimentation now demonstrates that PARP1 inhibit...

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Detalles Bibliográficos
Autores principales: Juncheng, Pan, Lafarge, Antoine, Kroemer, Guido, Castedo, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377245/
https://www.ncbi.nlm.nih.gov/pubmed/35979387
http://dx.doi.org/10.1080/2162402X.2022.2111915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377245/
https://www.ncbi.nlm.nih.gov/pubmed/35979387
http://dx.doi.org/10.1080/2162402X.2022.2111915

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