Obesity reduced survival with 5-fluorouracil and did not protect against chemotherapy-induced cachexia or immune cell cytotoxicity in mice

Fluorouracil/5-flourouracil (5FU) is a first-line chemotherapy drug for many cancer types; however, its associated toxicities contribute to poor quality of life and reduced dose intensities negatively impacting patient prognosis. While obesity remains a critical risk factor for most cancers, our und...

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Detalles Bibliográficos
Autores principales: VanderVeen, Brandon N., Cardaci, Thomas D., McDonald, Sierra J., Madero, Sarah S., Unger, Christian A., Bullard, Brooke M., Enos, Reilly T., Velázquez, Kandy T., Kubinak, Jason L., Fan, Daping, Murphy, E. Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377261/
https://www.ncbi.nlm.nih.gov/pubmed/35968771
http://dx.doi.org/10.1080/15384047.2022.2108306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377261/
https://www.ncbi.nlm.nih.gov/pubmed/35968771
http://dx.doi.org/10.1080/15384047.2022.2108306

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