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Obesity reduced survival with 5-fluorouracil and did not protect against chemotherapy-induced cachexia or immune cell cytotoxicity in mice
Fluorouracil/5-flourouracil (5FU) is a first-line chemotherapy drug for many cancer types; however, its associated toxicities contribute to poor quality of life and reduced dose intensities negatively impacting patient prognosis. While obesity remains a critical risk factor for most cancers, our und...
Autores principales: | VanderVeen, Brandon N., Cardaci, Thomas D., McDonald, Sierra J., Madero, Sarah S., Unger, Christian A., Bullard, Brooke M., Enos, Reilly T., Velázquez, Kandy T., Kubinak, Jason L., Fan, Daping, Murphy, E. Angela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377261/ https://www.ncbi.nlm.nih.gov/pubmed/35968771 http://dx.doi.org/10.1080/15384047.2022.2108306 |
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