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An integrated model of acinar to ductal metaplasia-related N7-methyladenosine regulators predicts prognosis and immunotherapy in pancreatic carcinoma based on digital spatial profiling

Acinar-to-ductal metaplasia (ADM) is a recently recognized, yet less well-studied, precursor lesion of pancreatic ductal adenocarcinoma (PDAC) developed in the setting of chronic pancreatitis. Through digital spatial mRNA profiling, we compared ADM and adjacent PDAC tissues from patient samples to u...

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Detalles Bibliográficos
Autores principales: Yang, Hao, Messina-Pacheco, Julia, Corredor, Andrea Liliam Gomez, Gregorieff, Alex, Liu, Jun-li, Nehme, Ali, Najafabadi, Hamed S., Riazalhosseini, Yasser, Gao, Bo, Gao, Zu-hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377277/
https://www.ncbi.nlm.nih.gov/pubmed/35979350
http://dx.doi.org/10.3389/fimmu.2022.961457