Targeting IKKε in Androgen-Independent Prostate Cancer Causes Phenotypic Senescence and Genomic Instability

Advanced prostate cancer will often progress to a lethal, castration-resistant state. We previously demonstrated that IKKε expression correlated with the aggressiveness of prostate cancer disease. Here, we address the potential of IKKε as a therapeutic target in prostate cancer. We examined cell fat...

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Detalles Bibliográficos
Autores principales: Gilbert, Sophie, Péant, Benjamin, Malaquin, Nicolas, Tu, Véronique, Fleury, Hubert, Leclerc-Desaulniers, Kim, Rodier, Francis, Mes-Masson, Anne-Marie, Saad, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Small Molecule Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377745/
https://www.ncbi.nlm.nih.gov/pubmed/34965959
http://dx.doi.org/10.1158/1535-7163.MCT-21-0519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377745/
https://www.ncbi.nlm.nih.gov/pubmed/34965959
http://dx.doi.org/10.1158/1535-7163.MCT-21-0519

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